Average pre-pulse inhibition (PPI) of the acoustic-star

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  • November 29, 2016
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The study aimed at understanding the psychoacoustic characteristics of tinnitus in individuals with auditory neuropathy spectrum disorder (ANSD). The results are based on a statistical analysis of the data compared to a normative database as calculated in Z scores, controlling for the factors of age, gender, IQ, and the like. Initial volume comparisons show a strong relationship between treatment and decrease in tinnitus intensity, with 57% of patients achieving successful treatment. Tinnitus laterality predictive performance of a particular index was assessed by increasing the cutoff or minimum magnitude of the aITD from 10 to 35 dB in 5-dB steps to determine its ROC curve. & Lipsitz, L. The subject group consisted of 16 ears of patients, in which 6 subjects were having tinnitus in both ears while 4 subjects were having tinnitus only in one ear. We induced tinnitus in mice by prolonged exposure to a loud mid-range tone, and behaviorally assayed whether mice exhibited a change in frequency discrimination acuity for tones embedded within the mid-frequency range and high-frequency range at 1, 4, and 8 weeks post-exposure.

Despite some limitations, there are arguments that the regional pattern of abnormal spontaneous activity we found could reflect a tinnitus-related cortical network. These mice exhibited impaired frequency discrimination both for tones in the mid-frequency range and high-frequency range. IMHO, using a single tone in an attempt to subliminally affect the audience is a bit of a clumsy technique by itself. They do, however, become sensitive to neighboring frequencies.

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